Introduction

Sperm cells, also known as sperms, are the male haploid gametes (spermatozoa) required for fertilization. In healthy individuals, sperms are typically concentrated in the seminiferous tubules of the testis where they undergo a series of developmental stages. They then travel through the epididymis, vas deferens, ejaculatory ducts, and penis to be discharged from the body. Sperms are produced from spermatogonia, the stem cells in the testis that differentiate into mature sperms through a process called spermiogenesis.

In addition to sperms, semen also contains round cells, which are either leucocytes (white blood cells) or immature germ cells. These cells are part of the body's immune system and play a crucial role in the prevention and clearance of infectious agents. In this article, the terminology used to describe the cells present in semen is discussed in detail, with specific focuses on the presence and interpretation of round cells in seminal fluid and their significance in relation to male fertility and health. The document also provides an overview of the methods used for the analysis and identification of round cells in semen, with a particular emphasis on their relevance in the context of fertility studies.

Term Definition

  • Sperm: The male fertilizing gamete, resulting from the differentiation of spermatogonia in the testis. It is typically concentrated in the seminiferous tubules, Epididymis, Vas Deferens, ejaculatory Ducts and Penile Orifices where it undergoes developmental stages.
  • SEM: An organ present in the male reproductive system consisting of the testis, epididymis, and vasa deferentia. Also called SEMINAL GLAND, the term is often used synonymously with "seminiferous tubules."
  • SPERMATOZOA: The male germ cells that result from the differentiation of spermatogonia in the testis. During spermatogenesis, these cells undergo a series of mitotic and meiotic divisions, eventually transforming into精子.
  • ROUND CELLS:
  • White blood cells: Leucocytes are blood cells that serve in fighting off infection.
  • Immature Germ Cells: Immature germ cells, specifically spermatogonia and spermatocytes, are non-spermatogenic germ cells found in the seminiferous tubules. They are the focus of this document.
  • Round cells represent the combined presence of leucocytes and mature germ cells and are collectively referred to as "round cells"in semen analysis.
  • These cells have a role in regulating the immune system and participate in preventing and clearing infectious agents via their phagocytic function.

Collection of Images

Here, you will find images that illustrate the morphology of round cells in semen. These images have been modified to enhance visibility and provide contextual information.

![Image of a seminiferous tubule showing numerous spermatogonia (yellow arrows)]
![Image of a seminiferous tubule with visible round cells (white arrows)]
![Image of a large phagocytic macrophage engulfing material (white arrow)]

Method of Collection

For the collection of images, a microscope was used to observe and capture the morphology of round cells in semen. Images were taken from various regions of the seminiferous tubules including the testis, epididymis, and ejaculatory ducts, to provide a comprehensive view of the round cells' occurrence in the male reproductive system.

Significance of Round Cells in Spermatozoozytozoospermia and Testicular Histology

In normozoospermia, the percentage of total spermatocytes is 40% according to the 2019 data. In the analysis of spermatogonia, the presence of 3-9% leucocytes can be observed. This indicates that in a normal context, round cells are not uncommon in the male reproductive system.

##, round cells, which are either leucocytes or immatures germ cells, play an essential role in the male reproductive system. They inhabit the seminiferous tubules, the epididymis, the vasa deferentia, and the ejaculatory ducts, where they are critical for regulating the immune systems and aiding in the prevention and clearing of infective agents. These cells may become more prominent in conditions such as bacterial infections and testicular diseases, indicating their relevance in spermatogenesis and overall health of the male reproductive system. The analysis of round cells in seminal fluid is an invaluable diagnostic technique for both the health care professional and for the patient seeking treatment for fertility problems. Understanding the significance and interpretation of these cells is crucial for optimizing reproductive outcomes and reducing不必要的 medical interventions.

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