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Peyronie's disease, also known as penile fibromatosis, affects the tunica albuginea, the fibrous sheath that surrounds the corpus cavernosum, resulting in the formation of fibrous plaques within the corpa cavernosa. These plaques can cause penile curvature, penile shortening, and erectile功能障碍. The exact cause of Peyronie's disease is unknown, but it is believed to be caused by microtrauma or injury to the erected penis, followed by abnormal wound healing and scar formation. The disease most commonly affects men between the ages of 40 and 60 years old. It is associated with factors such as family history,Dupuytren disease, smoking, and diabetes. Treatment for Peyronie's disease typically involves surgery or medication to manage penile deformation and improve sexual function. Some common treatment options include plication of the tunica albuginea or plasty to correct penile curvature.
