Wellbutrin, sold as Bupropion, is an antidepressant commonly prescribed to treat depression, seasonal affective disorder (SAD), and to aid in smoking cessation. Due to its mechanisms of action, the drug affects the levels of dopamine and norepinephrine in the brain, which are crucial for mood regulation and overall well-being. However, when withdrawal from wellbutrin occurs suddenly, patients may experience a range of symptoms that can be distressing and potentially harmful.
Wellbutrin withdrawal symptoms can begin as early as 24 to 48 hours after the last dose, and typically persist for several days to a couple of weeks. While many people do not experience significant withdrawal, others may suffer from moderate to severe withdrawal symptoms, including:
- Irritability and agitate – Patients may become irritable and feel like they are "wiggling off the couch."
- Anxiety and fearfulness – Many report feelings of panic or extreme fear when trying to quit wellbutrin.
- Mood swings and emotional instability – Depression, irritability, anger, or even mania may characterize withdrawal.
- Sleep disturbances – Insomnia or vivid dreams may become more common as the body readjusts to absence of wellbutrin.
- Difficulty sleeping or poor sleep hygiene – Lack of sleep becomes a common concern during withdrawal from wellbutrin.
It is important to note that these symptoms do not necessarily indicate a serious problem; they are simply side effects resulting from the body's attempt to adjust to absence of the drug. Despite the commonness of withdrawal symptoms, the wellbutrin tapering schedule, which involves increasing the dosage slowly over time and then gradually decreasing it, can help minimize these symptoms and facilitate a smoother transition off the medication.
If you are considering quitting wellbutrin, it is crucial to discuss your plans with a qualified healthcare professional. Your doctor can advise you on the best tapering schedule tailored to your specific needs, ensuring that you experience minimal discomfort or complications during the process.