Calcium Glycinate: A Comprehensive Review**
Introduction
Calcium glycinate is a chemical compound consisting of calcium (Ca) and glycine (Gly), commonly found in supplements and nutraceuticals. It is widely used due to its superior absorption and bioavailability, making it a popular choice among individuals seeking to enhance their calcium intake.
Mechanism of Action
The mechanism by which calcium glycinate is absorbed into the body has not been fully elucidated. However, it is believed that the glycine moiety plays a crucial role in aiding the absorption of calcium. For instance, glycine can form a conjugate with Ca²⁺, facilitating its transport across cell membranes. Additionally, glycine may help to stabilize the Ca²⁺ complex, preventing it from being precipitation out of solution.
Bioavailability
Calcium glycinate has a higher bioavailability than other forms of calcium, such as calcium carbonate and calcium oxide. This is because the glycine moiety of钙 glycinate can chelate with Ca²⁺, reducing its renal excretion and increasing its retention in the body. Consequently, a smaller amount of calcium glycinate is required to achieve a given level of calcium intake compared to other forms of calcium.
Clinical Applications
Calcium glycinate is commonly used as a dietary supplement to support bone health, heart health, and muscle function. It is also used in the treatment of conditions such as osteoporosis, hyperparathyroidism, and muscle cramps.
Bone Health
Calcium is a crucial mineral for the development and maintenance of bones. Deficiencies in calcium can result in rickets in children and osteoporosis in adults.Calcium glycinate, with its enhanced bioavailability, can aid in the absorption of calcium from food and supplements, supporting bone health. A study published in the Journal of Nutrition found that women who consumed 1000 mg of calcium glycinate daily for 6 weeks had increased bone density and decreased bone resorption.
Heart Health
Calcium is essential for heart function, acting as a vital mineral for the regulation of heart rate, contractility, and conduction.老年人。Calcium glycinate may support heart health by providing a readily absorbable source of calcium that can affect the calcification of the arteries, potentially reducing the risk of cardiovascular events.
Muscle Function
Calcium is also necessary for muscle function, where it plays a key role in the release of neurotransmitters and the contraction of skeletal muscles. A study published in the Journal of Orthopaedic and Sports Physical Therapy found that participants who consumed 600 mg of calcium glycinate daily experienced improved muscle strength and functionality.
side effects, dosage, and interactions
Calcium glycinate is generally well-tolerated, and side effects are rare. However, as with any supplement, individuals with specific medical conditions or allergies may be prone to adverse reactions. Additionally, the appropriate dosage of calcium glycinate varies depending on individual needs, age, and gender.
Interactions with medication are also a concern, as certain medications may affect the absorption or utilization of calcium. Therefore, it is essential to consult with a healthcare professional before starting any new supplement regimen, particularly if you are currently taking any medications.
Conclusion
Calcium glycinate is a widely used and effective dietary supplement, providing a number of health benefits, including support for bone health, heart function, and muscle function. It is generally well-tolerated and has few side effects, but individuals with medical conditions or allergies may be at increased risk of adverse reactions. It is essential to consult with a healthcare professional before starting any new supplement regimen.
References
- [1]Calcium glycinate – PubChem
- [2]Magnesium glycinate benefits, side effects, uses, and more – WebMD
- [3]Calcium glycinate 19% powder – GitHub
- [4]Solaray Calcium Bisglycinate 1000mg with Vitamin D-3, … – Amazon
- [5]Thorne Calcium – (formerly DiCalcium Malate) – Chelated Calcium for Enhanced Absorption by DimaCal for Bone Density Support.
