Introduction

Ketamine is a powerful anesthetic and sedative medication that has both legal and illegal uses. The duration of ketamine's effects in the body is influenced by several factors, such as the dosage, route of administration, individual differences in metabolism, and the presence of other substances like cocaine or ethanol. This article aims to provide a comprehensive overview of how long ketamine stays in the system, including information on detection times in various body fluids and the effects on the body.

metabolism and elimination

Ketamine is rapidly metabolized by the liver, with approximately 90% of the drug being excreted in the form of metabolites through the urinary system. The half-life of ketamine in adults is roughly 2.5 to 3 hours, meaning that the body eliminates half of the drug every 2.5 to 3 hours. This implies that the average elimination time for ketamine in a healthy adult is roughly three hours and 45 minutes.

Detection Times in Body Fluids

Urine

Ketamine and its代谢产物norKET can be detected in urine for up to several weeks after the last use, depending on the dosage and frequency of use. larger doses may be excreted in the urine for longer than smaller doses.

Blood

Blood tests for ketamine are relatively uncommon due to the short half-life of the drug, with ketamine detected in blood for up to 2.5 hours after it enters the bloodstream. A blood test is most effective within the first 24 hours after use.

Saliva

Ketamine can be detected in saliva for up to 48 hours after the last use.

Hair

Traces of ketamine can remain in the hair and hair follicles for up to 4 months after a single usage.

Breast Milk

There is limited data on how long ketamine can be detectable in breast milk, but it is never recommended to use ketamine while breastfeeding due to the potential risks to the nursing baby.

Effects on the Body

Ketamine can produce a variety of effects on the body, ranging from analgesia (pain relief) to delirium (disorientation). The duration of these effects depends on factors such as the dosage and route of administration.

Ketamine Withdrawal

With regular use, the body comes to depend on ketamine, and withdrawal symptoms can occur if the drug is suddenly stopped or cannot be obtained. These can include mental health symptoms such as depression, anxiety, irritability, and paranoia, as well as physical symptoms like gastrointestinal discomfort, Vision and hearing problems, increased heart rate, and intense cravings.

###, ketamine remains in the body for a variable period, depending on several factors. The duration of detection in body fluids ranges from a few days to several weeks, while the effects can last from a few minutes to several hours. Given the potential for both positive and negative effects, it is crucial to use ketamine responsibly and under medical supervision when necessary. Seeking professional help for addiction to ketamine is also highly recommended to avoid costly and potentially harmful consequences.